Is radical human life extension within reach for people alive today?

Shervin Pishevar · Jan 13, 2025

We will find cures to every known disease within roughly the next ten years, leaving accidents rather than disease as the cause of death

Merged quantum and AI compute at the scale of a million qubits will solve in hours problems that would otherwise take billions of years

Scope: ~10 year horizon

57:35 20VC: Shervin Pishevar on The Epic Uber War and What Really Happened in the Firing of Travis Kalanick | Raising $15BN to Win China | Why The Traditional Venture Capital Model is Dead | The Future of Quantum and How We Will Cure All Diseases in 10 Years

Harry Stebbings · Feb 17, 2025 · hedged

Diseases long taught to be incurable, such as MS, may in fact become curable through AI-driven drug and disease discovery

Scope: personal stake — his mother has MS

75:52 20VC: NVIDIA vs Groq: The Future of Training vs Inference | Meta, Google, and Microsoft's Data Center Investments: Who Wins | Data, Compute, Models: The Core Bottlenecks in AI & Where Value Will Distribute with Jonathan Ross, Founder @ Groq

Harry Stebbings · Feb 9, 2026

We will see real breakthroughs in treatments for conditions like multiple sclerosis that have previously been written off as bad luck

Scope: over the next ten years

79:44 20VC: Is SaaS Dead in a World of AI | Do Margins Matter Anymore | Is Triple, Triple, Double, Double Dead Today? | Who Wins the Dev Market: Cursor or Claude Code | Why We Are Not in an AI Bubble with Anish Acharya @ a16z

Anastasios Angelopoulos · Aug 3, 2026

AI will eradicate diseases one by one the way it is closing open problems in math, producing extraordinary human flourishing, but medicine is harder because it is not a closed system

Math is a closed system; medicine requires fast iteration in feedback loops on biological systems, which is the missing piece

Scope: contingent on cracking fast biological feedback loops

61:14 20VC: 70% of Neolabs Will Die | There Will be a $100BN US Open-Source Model | Data is a Trillion $ Market | Governments Cannot Regulate Models: It is Too Late | The Cyber Attacks to Come Will be Insane with Anastasios Angelopoulos @ Arena

Harry Stebbings · Aug 8, 2026 · speculative

There will be amazing discoveries for chronic conditions once assumed permanent, changing millions of lives

79:06 20VC: The AI Boom Will Create Enormous Roadkill: Who Wins & Loses | Why Founders Should Never Take Multi-Stage Money at Seed | Why Triple, Triple, Double, Double is Good Enough

Andrew Macdonald · Aug 17, 2026 · speculative

Humanity will solve all human disease at some point, making very long lifespans possible.

He has gained conviction on this as he's become more interested in longevity; he describes himself as a humanity bull.

Scope: unsure about literal immortality, but expects very long life; no timeline given

58:18 20VC: Uber President on The Untold Uber Stories: Travis, China and Self-Driving | Why Autonomy Is Existential | How to Beat DoorDash to #1 in Food with Andrew MacDonald

Mike Krieger · Mar 3, 2025

AI's potential to accelerate drug discovery and extend healthy lifespan is huge, and today's models already deliver step changes in parts of the pipeline

Novo Nordisk went from roughly fifteen weeks to twenty minutes on clinical trial reports using Claude, and that is with today's models

Scope: explicitly not claiming years compressed to minutes — years of prior research preceded that step; it speeds one point in the process, not the whole

61:22 20VC: Anthropic CPO Mike Krieger: Where Will Value Be Created in a World of AI | Have Foundation Models Commoditized | When Do Model Providers Become Application Providers | What Anthropic Learned from Deepseek

Richard Socher · Apr 18, 2025

Longevity is massively underrated, and the AI-plus-bio path to improving it is the most exciting realistic development of the next ten years

People who are snarky about not wanting longevity all change their minds days before death when they're in pain and regretting drinking and poor sleep

56:57 20VC: Foundation Models: Who Wins & Who Loses | How Economies and Labour Markets Need to Change in a World of AI | China vs the US in an AI Race: What You Need to Know | Rich Socher, Founder @ You.com

Jerry Murdock · Feb 28, 2026 · speculative

Autonomous agents and AI may enable radical life extension

Invokes the Big Daddy character's line about living forever as the analogue for what AI could deliver

Scope: framed as a personal hope

56:51 20VC: Why Cursor is Dead | An AI Tsunami is Coming & You Need to Prepare | Systems of Record Become Valueless Databases with Agents | Is This The End of Tech Private Equity with Jerry Murdock, Co-Founder of Insight Partners

Harry Stebbings · Mar 2, 2026

AI and longevity research will drive major advances in treating diseases like MS

64:45 20VC: Monday.com CEO on Is SaaS Dead: Will Everything Be Vibe Coded | Will Systems of Record Become Valueless Databases in an Agentic World | Will LLMs Own the Value in the Application Layer with Eran Zinman

Jerry Murdock · Feb 28, 2026 · hedged

Life-extension progress is compounding such that surviving another five years buys you at least another five years

Advances arrive fast enough that each five years of survival extends the horizon further

57:19 Each five years of survival buys five more

Jonathan Ross · Feb 17, 2025 · speculative

If significantly slowing or stopping aging is physically possible, it will be achieved suddenly within the next ten years — a 'Mounjaro moment' — but whether it is possible at all is unknown

Mounjaro came out of nowhere and suddenly something just worked; wear and tear may make aging irreducible, so the conditional has to stay in

70:36 Sudden breakthrough within a decade if aging reversal is physically possible

Harry Stebbings · Feb 17, 2025 · hedged

Given coming advances in medical research, it is almost certainly possible to extend human longevity by at least sixty years

He can't see how the advances coming in medical research wouldn't make it possible

71:18 Medical advances will extend longevity by decades